Ciprofloxacin hydrochloride hydrate
- CAS No.
- 86393-32-0
- Chemical Name:
- Ciprofloxacin hydrochloride hydrate
- Synonyms
- Ciprofloxacin hydrochloride CRS;Monohydrochloride monohydrate;Ceprimax;Oftacilox;Ciprooxacin HCL;Ciprofloxcin hcl;oride Monohydrate;Ciprofloxaicin HCL;Ciprofloxacin-d8 HCl;CIPROFLOXACIN HCL USP
- CBNumber:
- CB4740508
- Molecular Formula:
- C17H21ClFN3O4
- Molecular Weight:
- 385.82
- MDL Number:
- MFCD00079044
- MOL File:
- 86393-32-0.mol
| Melting point | 318-320 °C |
|---|---|
| RTECS | VB1993800 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol, practically insoluble in acetone, in ethyl acetate and in methylene chloride. |
| color | White to Light yellow |
| PH | pH (25g/l, 25℃) 3.0～4.5 |
| Water Solubility | Soluble in water (35mg/ml). |
| Merck | 14,2314 |
| InChIKey | DIOIOSKKIYDRIQ-UHFFFAOYSA-N |
| CAS DataBase Reference | 86393-32-0(CAS DataBase Reference) |
| FDA UNII | 4BA73M5E37 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2933595960 |
Ciprofloxacin hydrochloride hydrate price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR1044 | Ciprofloxacin HCl Pharmaceutical Secondary Standard; Certified Reference Material | 86393-32-0 | 1g | $114 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1134335 | Ciprofloxacin hydrochloride United States Pharmacopeia (USP) Reference Standard | 86393-32-0 | 400mg | $436 | 2024-03-01 | Buy |
| TCI Chemical | C2227 | Ciprofloxacin Hydrochloride Monohydrate >98.0%(HPLC)(T) | 86393-32-0 | 5g | $57 | 2024-03-01 | Buy |
| TCI Chemical | C2227 | Ciprofloxacin Hydrochloride Monohydrate >98.0%(HPLC)(T) | 86393-32-0 | 25g | $149 | 2024-03-01 | Buy |
| Alfa Aesar | J61970 | Ciprofloxacin hydrochloride | 86393-32-0 | 5g | $71.6 | 2024-03-01 | Buy |
Ciprofloxacin hydrochloride hydrate Chemical Properties,Uses,Production
Chemical Properties
Pale yellow, crystalline, slightly hygroscopic powder.
Uses
Fluoroquinolone antibacterial.
Uses
Ciprofloxacin hydrochloride has been suggested as a treatment for a wide range of infections caused by susceptible organisms including infections of urinary, respiratory, and gastrointestinal tracts, gonorrhoea and septicaemia. Nalidixic acid analogue.
Application
Ciprofloxacin hydrochloride hydrate is a broad-spectrum antibiotic that inhibits bacterial DNA gyrase and blocks DNA synthesis and replication, resulting in bacterial death. It has strong antibacterial activity against Escherichia coli, Klebsiella and other Enterobacteriaceae; the antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae is better than norfloxacin and pefloxacin.
Definition
ChEBI: The monohydrate form of ciprofloxacin monohydrochloride.
brand name
Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).
General Description
Ciprofloxacin HCl is a fluoroquinolone antibiotic agent, which shows a broad spectrum of antibacterial activity against gram positive and gram negative bacteria.
in vitro
Ciprofloxacin (hydrochloride monohydrate) is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. Ciprofloxacin (hydrochloride monohydrate) (CIP) shows potent activity against Y. pestis with MIC 90 of 0.03 μg/mL.
in vivo
Ciprofloxacin (hydrochloride monohydrate) (1 mg/L) induces glutathione-S-transferase (GST) activity, in contrast with inhibited GST and Catalase (CAT) of larvae exposed to enrofloxacin. Ciprofloxacin (hydrochloride monohydrate) (≥10 μg/L) is ecotoxic for development, growth, detoxifying, and oxidative stress enzymes in anuran amphibian larvae. In a murine model of pneumonic plague, Ciprofloxacin (hydrochloride monohydrate) (30 mg/kg, i.p.) results in a drug exposure which is similar to the drug exposure observed in human following a 500 mg dose of oral Ciprofloxacin (hydrochloride monohydrate). Intraperitoneal Ciprofloxacin (hydrochloride monohydrate) reduces the lung bacterial load compare to controls treated with intraperitoneal PBS.
Ciprofloxacin hydrochloride hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 1072 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 | bruce@xrdchem.cn | CHINA | 566 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Shaanxi Yikanglong Biotechnology Co., Ltd. | 17791478691 | yklbiotech@163.com | CHINA | 296 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
View Lastest Price from Ciprofloxacin hydrochloride hydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-07 | Ciprofloxacin hydrochloride hydrate
86393-32-0
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2024-03-15 | Ciprofloxacin hydrochloride hydrate
86393-32-0
|
US $35.00-25.00 / kg | 1kg | 99.8% | 200tons/year | Sigma Audley | |
 |
2023-09-20 | Ciprofloxacin HCl hydrate
86393-32-0
|
US $0.00 / kg | 1kg | 99% | 20tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Ciprofloxacin hydrochloride hydrate
86393-32-0
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Ciprofloxacin hydrochloride hydrate
86393-32-0
- US $35.00-25.00 / kg
- 99.8%
- Sigma Audley
-
- Ciprofloxacin HCl hydrate
86393-32-0
- US $0.00 / kg
- 99%
- Hebei Yanxi Chemical Co., Ltd.